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$IONS

Ionis Pharmaceuticals, Inc. Common Stock

XNASHealth CarePharmaceutical Preparations

$54.84+1.21%+$0.6550Prev $54.19LIVE Full chart Live alerts
No recent price bars, the chart lights up when IONS starts printing.

Why is IONS up today? It is at $54.84 (+1.21%), and our scanner flagged it 59 times on unusual volume this month. See the catalyst behind the move, real-time alerts the moment IONS spikes, and full due diligence on IONS — key stats, earnings, dilution and insider activity. Free.

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Our scanner flagged $IONS 59 times in the last 30 days. Create a free account to track $IONS, build a watchlist, and get instant unusual-volume alerts — plus 5 free premium days, no card needed.

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Key Stats

Price & performance
Price
$54.84
Change today
+1.21%
Previous close
$54.19
52-week range
$40.03 – $86.74
Valuation & dividend
Market cap
$9.01B
Ownership & volume
Shares outstanding
166.2M
SEC · as of 2026-07-23 · 14d
Insider ownership
2.4%
DEF 14A · 2026-04-23
Institutional own.
99.9%
Total held
100.0%
Short interest
20.0M
▲ +15% vs prior · as of 2026-07-15
Days to cover
3.7d
Avg daily volume
2.5M
Classification
Sector
Health Care
Industry
Pharmaceutical Preparations
Exchange
XNAS
Relative volumevs this time of day
5m
0.4x
15m
0.3x
1h
0.5x
1D
0.1x

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Why is $IONS up today?

Here is the latest on IONS from our scanner (live price and day move above). We have not detected an unusual-volume catalyst for IONS today, so it is trading in line with its recent range. The moment our scanner flags unusual activity, the reason will appear here.

Likely catalystQuarterly report (10-Q), from the latest SEC filing. Read it →
Why is $IONS moving? →▶ Replay the moveAuto-generated from live scanner data. Not investment advice.
Trading profile⚡ Ultra-low floatShortableEasy to borrowNo SSRBorrow via Alpaca · SSR from Reg SHO 201

Insiders

2 open-market buys3 buys, 17 sells last 3 months (21/127 over 12 months)
Show 12 recent transactions
InsiderActionShares% of positionOwns afterValueDate
Hayden Michael R
Director
Bought (open market)+5Kadded 26%24K$258K
at $51.60
Jul 31, 26
Hayden Michael R
Director
Bought (open market)+15Kadded 100%19K$801K
at $53.38
Jul 30, 26
Berthelsen Spencer R
Director
Other5Kadded 3.3%161Kn/aJul 15, 26
Herman Joan E
Director
Other5Kadded 11%51Kn/aJul 15, 26
Kordasiewicz Holly B.
Officer
Sold (automatic/other)-362sold 1.6%22K$31K
at $84.30
Jul 7, 26
Diaz Allene M.
Director
Sold (automatic/other)-10Ksold 73%4K$864K
at $85.42
Jul 7, 26
Diaz Allene M.
Director
Other10Kadded 100%14K$476K
at $47.11
Jul 7, 26
Bennett C Frank
Officer
Sold (automatic/other)-6Ksold 6.9%75K$463K
at $83.58
Jul 7, 26
Bennett C Frank
Officer
Acquired (grant/award)+15Kn/a15Kn/aJul 7, 26
Bennett C Frank
Officer
Sold (automatic/other)-15Kn/an/a$1.3M
at $85.46
Jul 7, 26
Klein Joseph Iii
Director
Sold (automatic/other)-12Ksold 51%11K$910K
at $79.04
Jul 1, 26
Klein Joseph Iii
Director
Other12Kadded 100%23K$460K
at $39.94
Jul 1, 26

Recent Form-4 filings via Nasdaq. Open-market buys are the signal worth watching. Grants and automatic (10b5-1) sells are routine. “% of position” is the share of that insider’s own holding the trade moved. Not investment advice.

$IONS Sentiment

Bullish
Bearish67Bullish
📰 News: 3 bull · 1 bearToday: +1.2%👥 Community: 0 bull · 0 bear

Blend of news sentiment, today’s move, and community votes. Not investment advice.

$IONS Activity

News, unusual-volume alerts, AI-trader trades and community chatter — the whole story, newest first.

Alert· 1d ago -1.03%
$IONS moved -1.03% in 1 min (Level 1) at 4:00 PM ET
at $54.69
Alert· 1d ago 5.2× RVOL
IONS hit 5.172x RVOL at 1:52 PM ET
at $54.96
Alert· 2d ago +1.9% vs EMA
IONS 200EMA (5m) Trending · 76 bars · L3 · +1.87% above EMA · slope +0.35%
at $54.12
Alert· 2d ago +0.8% vs EMA
IONS 50EMA (5m) Trending · 87 bars · L3 · +0.77% above EMA · slope +0.69%
at $54.12
Alert· 2d ago +1.7% vs EMA
IONS 200EMA (1m) Trending · 304 bars · L5 · +1.69% above EMA · slope +0.22%
at $54.50
Alert· 2d ago +1.7% vs EMA
IONS 200EMA (1m) Trending · 304 bars · L5 · +1.69% above EMA · slope +0.22%
at $54.50
News· The Motley Fool· 2d ago Bullish
Ionis Pharmaceuticals Director Hayden Buys $1.1 Million Shares. What Does This Mean for Investors?
Alert· 2d ago 11.3× RVOL
IONS hit 11.304x RVOL at 3:10 PM ET
at $54.02
Alert· 2d ago +0.8% vs EMA
$IONS near 200 EMA: +0.83% from 200 EMA at 2:11 PM ET
at $53.82
Alert· 2d ago 3.0× RVOL
IONS hit 2.958x RVOL at 2:11 PM ET
at $53.82
Alert· 2d ago 3.7× RVOL
IONS hit 3.731x RVOL at 12:15 PM ET
at $53.35
Alert· 5d ago -1.27%
$IONS moved -1.27% in 1 min (Level 1) at 4:44 PM ET
at $52.78
Alert· 5d ago 3.2× RVOL
IONS hit 3.231x RVOL at 3:06 PM ET
at $51.73
Alert· 5d ago -1.8% vs EMA
$IONS near 200 EMA: -1.85% from 200 EMA at 11:51 AM ET
at $51.42
Alert· 5d ago 10.3× RVOL
IONS hit 10.334x RVOL at 11:51 AM ET
at $51.42
Alert· 6d ago 6.6× RVOL
IONS hit 6.581x RVOL at 11:20 AM ET
at $51.79
Alert· 6d ago 21.9× RVOL
IONS hit 21.865x RVOL at 3:33 PM ET
at $53.02
News· SEC EDGAR· 7d ago
IONIS PHARMACEUTICALS INC filed a Quarterly report (10-Q)
Alert· 7d ago 2.1× RVOL
IONS hit 2.131x RVOL at 1:16 PM ET
at $54.56
News· SEC EDGAR· 8d ago
IONIS PHARMACEUTICALS INC: Ionis reports second quarter 2026 financial results and highlights progress on key programs
Alert· 8d ago 2.0× RVOL
IONS hit 2.000x RVOL at 3:24 PM ET
at $54.90
Alert· 8d ago -1.0% vs EMA
$IONS near 200 EMA: -1.00% from 200 EMA at 2:02 PM ET
at $54.32
Alert· 8d ago 2.0× RVOL
IONS hit 2.000x RVOL at 2:02 PM ET
at $54.32
News· GlobeNewswire Inc.· 8d ago Bearish
Ionis Pharmaceuticals, Inc. (IONS) Faces Investor Scrutiny After Surprise Trial Failure Drives Stock Down 23% – HBSS
Alert· 8d ago -0.4% vs EMA
$IONS near 200 EMA: -0.41% from 200 EMA at 11:29 AM ET
at $55.26
Alert· 8d ago 4.6× RVOL
IONS hit 4.578x RVOL at 11:29 AM ET
at $55.26
Alert· 9d ago 4.2× RVOL
IONS hit 4.209x RVOL at 10:57 AM ET
at $54.70
Alert· 12d ago +0.0% vs EMA
$IONS near 200 EMA: +0.04% from 200 EMA at 2:00 PM ET
at $56.91
Alert· 12d ago 4.7× RVOL
IONS hit 4.713x RVOL at 2:00 PM ET
at $56.91
News· GlobeNewswire Inc.· 22d ago Bullish
Oligonucleotide CDMO Market to Reach USD 9.87 Billion by 2031 as RNA-Targeted Drug Pipelines Expand
News· SEC EDGAR· 27d ago
IONIS PHARMACEUTICALS INC filed an 8-K: Regulation FD Disclosure
News· SEC EDGAR· 27d ago
IONIS PHARMACEUTICALS INC filed an 8-K: Regulation FD Disclosure, Other Material Event
News· GlobeNewswire Inc.· 30d ago Bullish
Transthyretin Amyloidosis Treatment Market Size to Reach USD 35.10 Billion by 2035, Growing at a 14.64% CAGR | SNS Insider

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IONS stock FAQ

Why is $IONS up today?

Here is the latest on IONS from our scanner (live price and day move above). We have not detected an unusual-volume catalyst for IONS today, so it is trading in line with its recent range. The moment our scanner flags unusual activity, the reason will appear here.

What is the IONS stock price today?

IONS last traded at $54.84, up 1.21% on the day. The price and chart above update live during market hours (4 AM to 8 PM ET).

Where can I see live IONS alerts?

The IONS Live Alerts panel on this page streams real-time unusual volume (RVOL), momentum, halt and 200-EMA alerts from our scanner the moment they fire. Our scanner has flagged IONS 59 times in the last 30 days.

What exchange is IONS on?

IONS (Ionis Pharmaceuticals, Inc. Common Stock) trades on XNAS, with a market cap of about $9.01B in the PHARMACEUTICAL PREPARATIONS sector.

Is IONS good for day trading?

That depends on your strategy and risk. Day traders look for volume, volatility and a clear trend. Use the live chart, RVOL alerts and 200-EMA context on this page to judge IONS for yourself. This is not investment advice.

Live data from TheDesperateTrader scanner. Not investment advice.